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COA & testingJuly 25, 20267 min read

How to Read a Peptide Certificate of Analysis (COA)

Understand identity, purity, quantity, analytical methods, dates, and the important limitations of a peptide COA.

Educational content only

This article concerns laboratory research materials. It is not medical advice and does not provide instructions for human or veterinary use.

01

Match the document to the product

Compare the product name, lot or batch identifier, sample code, report date, and testing laboratory with the material being reviewed.

02

Identity and purity are different

Identity testing helps determine what substance is present. Purity estimates the proportion represented by the target material under the stated method.

03

Look at the analytical methods

COAs may reference methods such as high-performance liquid chromatography or mass spectrometry. Each method answers a particular question and has limitations.

04

Review quantity and other reported tests

Purity and quantity are not interchangeable. Sterility, endotoxin, residual solvents, and water content are separate tests and should not be assumed.

05

A practical COA checklist

Check the sample name, lot identifier, laboratory, report date, methods, identity, purity, analyzed quantity, verification features, and disclosures.

06

The key takeaway

A COA is evidence for the specific sample and tests shown—not an all-purpose guarantee. Avoid conclusions the report does not support.

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